The emergence of the importance of such phenomena as alternative RNA processing, regulatory RNAs, and RNA-mediated enzymatic mechanisms to the regulation of gene expression in cells, along with the recognition of the contributions of RNA to disease pathogenesis and normal development, have made an understanding of the field of RNA biology essential to all life science disciplines. It is the goal of WIREs RNA to provide comprehensive, up-to-date, and coherent coverage of this interesting and growing field, providing a framework for both RNA experts and interdisciplinary researchers to not only gain perspective in areas of RNA biology, but to generate new insights and applications as well. Major topics to be covered are: RNA Structure and Dynamics; RNA Evolution and Genomics; RNA-Based Catalysis; RNA Interactions with Proteins and Other Molecules; Translation; RNA Processing; RNA Export/Localization; RNA Turnover and Surveillance; Regulatory RNAs/RNAi/Riboswitches; RNA in Disease and Development; and RNA Methods.

随着替代 RNA 加工、调节性 RNA 和 RNA 介导的酶促机制等现象对细胞基因表达调控的重要性逐渐显现，以及 RNA 对疾病发病机制和正常发育的贡献得到认可，了解 RNA 生物学领域已成为所有生命科学学科的必备知识。WIREs RNA 的目标是全面、最新、连贯地报道这一有趣且不断发展的领域，为 RNA 专家和跨学科研究人员提供一个框架，使他们不仅可以了解 RNA 生物学领域，还可以产生新的见解和应用。主要涵盖的主题包括：RNA 结构和动力学；RNA 进化和基因组学；基于 RNA 的催化作用；RNA 与蛋白质和其他分子的相互作用；翻译；RNA 加工；RNA 输出/定位；RNA 周转和监测；调节性 RNA/RNAi/核糖开关；RNA 在疾病和发育中的作用；以及 RNA 方法。

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