Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.

Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.

Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.

《计算生物学和化学》发表计算生命科学所有领域的原创研究论文和评论文章。特别欢迎在核酸和蛋白质序列研究、分子进化、分子遗传学（功能基因组学和蛋白质组学）、生物特定或化学生物学特定建模的理论和实践以及核酸和蛋白质的结构生物学等领域做出具有主要计算成分的高质量研究贡献。生物信息学、系统生物学、生态学、计算药理学、代谢、生物医学工程、流行病学和统计遗传学领域的极高质量研究工作也将受到考虑。

鉴于其固有的不确定性，应彻底验证蛋白质建模和分子对接研究。在没有实验结果进行验证的情况下，应使用分子动力学模拟以及详细的自由能计算等作为补充技术来支持主要结论。提交没有额外生物学见解的过早建模练习将不予考虑。

评论文章通常由编辑委托撰写，未经明确邀请不得提交给期刊。但是，欢迎潜在作者发送简短（一到三页）的概要，编辑将对其进行评估。

该刊已被国际权威数据库SCIE收录，该刊致力于发表经过严格同行评审的高质量原创文章，反映生物-计算机：跨学科应用领域的新进展、新技术、新成果，促进该领域科研交流和科研成果转化。该刊2023年影响因子为2.6，平均审稿速度为 约15.0个月 ，近四年来没有被列入预警名单。如果您需要投稿发表服务及指导，可以联系我们的客服老师，我们专业专注服务期刊投稿协助10年，为您提供期刊投稿个性化定制服务，并且我们确保严格保密您的个人信息及稿件内容。